Medications Can Cause Psych Adverse Effects

A number of medications intended to treat psychiatric disorders are themselves capable of causing psychiatric adverse effects. Unfortunately, these medication-induced adverse effects can be mistaken for a lack of therapeutic efficacy, leading to increased dose prescribing, leading to even more adverse effects. In addition, a number of medications not intended to treat psychiatric disorders are capable of causing psychiatric adverse effects. Following are some general catageories of medications that fall into these categories.

Medication Indication Severe Adverse Effect
Accutane cystic acne depression, headaches, psychosis, seizures, suicide
Adderall attention deficit, hyperactivity depression, seizures
Ambien (zolpidem) insomnia amnesia, anxiety, cognitive impairment, depression, drowsiness, sleepwalking, sleep driving, worsening of depression, suicidal thoughts.
Chantix smoking cessation suicidal thoughts
estrogen hormone deficiency, regulation of menstruation depression
Duragesic (fentanyl) pain control Somnolence, insomnia, confusion, asthenia, dizziness, nervousness, hallucinations, anxiety, depression, euphoria, tremor, abnormal coordination, speech disorder, abnormal thinking, abnormal gait, abnormal dreams, agitation, paresthesia, amnesia, syncope, paranoid reaction
Interferons viral hepatitis agitation, depression, headache, suicidal thought, drug-seeking behavior
Lariam malaria depression, psychosis
Lamictal bipolar disorder, seizure disorder depression
Lupron GnRH children with central precocious puberty, advanced prostate cancer Memory disorder, Mood swings, Nervousness
Meridia (sibutramine) obesity depression
Reglan gastric dysmotility depression, suicidal thought
SSRI: Prozac, Paxil, Zoloft depression aggitation, irritability, seizures, psychosis, suicide
Reserpine hypertension Anorexia, Dizziness, Nausea, Vomiting, Concentration Difficulty, Nervousness, Nightmares
Xanax anxiety disorders Agitation, mental confusion, depression, headache, irritability, nervousness, slurred speech, sleep disturbances, euphoria, lethargy, stupor.